Gene Therapies Could Give Superior Mesothelioma Treatments in Comparison to Radiation Therapy
Posted on 16 Jul 2009 | Tagged as: Health, University of Science
Oncologists and other cancer doctors determine what kind of treatment to administer for every patient. There are many options. There exists no regular treatment option for mesothelioma sufferers. This is because of the relative rareness of the disease, the high mortality rate and low treatment success rate, and the few scientific studies to provide meaningful statistics.
The prospects for mesothelioma patients have been grim, but doctors have recently made progress. Customary treatments for cancer are surgery (removing the tumor and the tissue that surrounds it), chemotherapy (poisoning cancerous cells) and radiation (killing cancer cells with radiation) Each one of these methods have problems. Traditional radiation therapy has not worked well with mesothelioma patients. Researchers are looking for ways of aiming radiation directly at the tumor in hopes that this will result in less damage to healthy tissue.
Surgery removes the mesothelial tissue around the tumor. This surgery is extensive and it is not clear how much the patient benefits. Common chemotherapy drugs that work on other types of cancer usually do not work on mesothelioma, and combinations of chemotherapy agents have been tried, but without much success. As with radiation, research is going toward controlling the physical location of the treatment with emphasis on the pleural cavity.
The death rate for mesothelioma is so high that many of even the most sophisticated techniques in cancer treatment are tried out on patients. Such treatments include anti-angiogenesis drugs like thalidomide and biologic therapies agent interleukin 2. Pemetrexed (Alimta) is a new drug that has shown results in extending life.
Before acting, oncologists review the stage of mesothelioma, position of the tumor, and age and health status of the patient. Two therapies that are extremely cutting-edge in fighting cancer are called photodynamic and gene therapy. Clinical trials using these techniques are being offered to some of those who have mesothelioma.
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